Recurrent IgA nephropathy in the renal allograft: not a benign condition.

نویسندگان

  • Jürgen Floege
  • Hermann Josef Gröne
چکیده

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1. Briganti EM, Russ GR, McNeil JJ et al. Risk of renal allograft loss from recurrent glomerulonephritis. N Engl J Med 2002; 347: 103–109 2. Odum J, Peh CA, Clarkson AR et al. Recurrent mesangial IgA nephritis following renal transplantation. Nephrol Dial Transplant 1994; 9: 309–312 3. Ortiz F, Gelpi R, Koskinen P et al. IgA nephropathy recurs early in the graft when assessed by protocol biopsy...

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Recurrence of the original disease is now the third most frequent cause of allograft loss at 10 years after transplantation in patients with underlying glomerulonephritis. IgA nephropathy (IgAN), the most common type of glomerulonephritis, histologically recurs in up to 60% of the patients. Initially considered to be a relatively benign phenomenon, several studies, which included a total of alm...

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Recurrence of glomerulonephritis (GN) and newly occurring GN (de novo GN) in the transplanted kidney are a frequent cause of allograft loss at 10 years [1] (Table 1). For example, studies in large US databases found a recurrence of the underlying disease in 3–8% of the patients [2, 3]. However, these retrospective analyses are biased by many confounding factors, such as the enormous disparity i...

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During a 14-month period (Dec. 1990-Jan. 1992) , renal biopsies were performed on 105 patients with suspected glomerular disease. All specimens were processed for light microscopy (L.M) and immunoflourescence. Work-up revealed 21 patients to suffer a systemic glomerular disease and glomerular disease was found to be primery in 85 cases. Predominant IgG deposition was noted in 71 cases with prim...

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عنوان ژورنال:
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

دوره 28 5  شماره 

صفحات  -

تاریخ انتشار 2013